What is a potential long-term consequence of untreated rheumatoid arthritis?

What is a potential long-term consequence of untreated rheumatoid arthritis?

• A. Joints become stronger over time.
• B. No impact on function.
• C. Potential permanent joint damage or deformity due to chronic inflammation.
• D. It resolves spontaneously.

Answer: (C)

Chronic autoimmune inflammation in rheumatoid arthritis gradually damages the joints if it isn’t controlled. The inflamed synovium thickens and can form pannus, which attacks cartilage and bone, leading to irreversible joint damage and deformity over time. This is why the long-term consequence is permanent joint damage or deformity due to ongoing inflammation. Joints do not become stronger; untreated RA generally worsens function, not improves it. The condition also does not typically resolve on its own, and it often requires treatment to prevent these outcomes. Early, aggressive therapy aims to suppress inflammation and protect joint structure.

Chronic autoimmune inflammation in rheumatoid arthritis gradually damages the joints if it isn’t controlled. The inflamed synovium thickens and can form pannus, which attacks cartilage and bone, leading to irreversible joint damage and deformity over time. This is why the long-term consequence is permanent joint damage or deformity due to ongoing inflammation. Joints do not become stronger; untreated RA generally worsens function, not improves it. The condition also does not typically resolve on its own, and it often requires treatment to prevent these outcomes. Early, aggressive therapy aims to suppress inflammation and protect joint structure.