NAFLD is best described as

NAFLD is best described as

• A. A metabolic liver condition characterized by excessive triglyceride accumulation in hepatocytes without significant alcohol intake
• B. Liver disease caused by chronic alcohol abuse
• C. A viral infection of the liver
• D. A rare genetic liver disease

Answer: (C)

Nonalcoholic fatty liver disease is a metabolic liver condition defined by excess fat accumulating in liver cells, specifically triglycerides, in people who drink little or no alcohol. This fat buildup arises from metabolic factors like insulin resistance, obesity, and components of the metabolic syndrome, rather than from alcohol or infection. The situation can range from simple fat accumulation (steatosis) to inflammation and damage (nonalcoholic steatohepatitis), which may progress to fibrosis or cirrhosis over time. It’s distinct from alcoholic liver disease, which is driven by alcohol intake, and from viral hepatitis, which is caused by viral infection.

Nonalcoholic fatty liver disease is a metabolic liver condition defined by excess fat accumulating in liver cells, specifically triglycerides, in people who drink little or no alcohol. This fat buildup arises from metabolic factors like insulin resistance, obesity, and components of the metabolic syndrome, rather than from alcohol or infection. The situation can range from simple fat accumulation (steatosis) to inflammation and damage (nonalcoholic steatohepatitis), which may progress to fibrosis or cirrhosis over time. It’s distinct from alcoholic liver disease, which is driven by alcohol intake, and from viral hepatitis, which is caused by viral infection.