GLP-1 receptor agonists have what dual clinical use?

GLP-1 receptor agonists have what dual clinical use?

• A. Type 2 diabetes and weight management
• B. Type 1 diabetes and weight management
• C. Gestational diabetes and obesity
• D. Hypoglycemia and dehydration

Answer: (A)

GLP-1 receptor agonists mimic the incretin GLP-1, boosting insulin secretion in a glucose-dependent manner and suppressing glucagon, which helps lower blood sugar. They also slow gastric emptying and act on brain centers to increase satiety, leading to weight loss. These effects make them useful for managing type 2 diabetes and for weight management. They’re not used for type 1 diabetes because there’s little endogenous insulin to enhance, and they aren’t a standard dual-use therapy for gestational diabetes or dehydration.

GLP-1 receptor agonists mimic the incretin GLP-1, boosting insulin secretion in a glucose-dependent manner and suppressing glucagon, which helps lower blood sugar. They also slow gastric emptying and act on brain centers to increase satiety, leading to weight loss. These effects make them useful for managing type 2 diabetes and for weight management. They’re not used for type 1 diabetes because there’s little endogenous insulin to enhance, and they aren’t a standard dual-use therapy for gestational diabetes or dehydration.