GLP-1 receptor agonists are exemplified by Exenatide and Dulaglutide.

GLP-1 receptor agonists are exemplified by Exenatide and Dulaglutide.

• A. They are not used clinically
• B. They are exemplified by Exenatide and Dulaglutide
• C. They inhibit SGLT2
• D. They do not affect glucose levels

Answer: (B)

GLP-1 receptor agonists are drugs that mimic the action of the natural incretin hormone GLP-1, enhancing glucose-dependent insulin release, suppressing glucagon, and slowing gastric emptying to help lower blood glucose. Exenatide and Dulaglutide are well-known, clinically used examples of this class, so stating that they exemplify GLP-1 receptor agonists is correct. This class is distinct from SGLT2 inhibitors, which means these drugs do not inhibit SGLT2, and they do affect glucose levels by improving glycemic control. They are not used as a nonexistent therapy; they are actively used to treat type 2 diabetes and often aid in weight loss as well.

GLP-1 receptor agonists are drugs that mimic the action of the natural incretin hormone GLP-1, enhancing glucose-dependent insulin release, suppressing glucagon, and slowing gastric emptying to help lower blood glucose. Exenatide and Dulaglutide are well-known, clinically used examples of this class, so stating that they exemplify GLP-1 receptor agonists is correct. This class is distinct from SGLT2 inhibitors, which means these drugs do not inhibit SGLT2, and they do affect glucose levels by improving glycemic control. They are not used as a nonexistent therapy; they are actively used to treat type 2 diabetes and often aid in weight loss as well.